UK and Italy: Medical Genetic Analysts - GlaxoSmithKline
Employer: GlaxoSmithKline
Location: United Kingdom
Date: Apr 30, 2007
Job Description
Description:
Medical Genetic Analysts - GlaxoSmithKline
Locations: Harlow - Essex, West London, Southeast England and Verona, Italy
GlaxoSmithKline (GSK) currently has an opportunity for a Medical Genetic Analysts to work at their sites in Harlow - Essex, West London, Southeast England and Verona, Italy
At GSK, one of the world's leading healthcare businesses, we discover, develop and produce products that help people live longer, do more and feel better
Job Details:
Medical Genetics (MedGen) is based within Clinical Pharmacology and Discovery Medicine Division with responsibility for a wide range of human research programs combining genetics, and clinical imaging to identify new therapeutic targets, identify biomarkers of disease progression, and response to medicines to support GSK drug development
MedGen has the accountability for the GSK Medical collections in complex diseases of high priority to the Centre for Excellence Drug Discovery (CEDDs)/Medicines Development Centres (MDCs). These collections include large family, case/control and population-based studies through collaborations with a worldwide network of leading physicians, and access to public and propriety data sets. MedGen's role is in the collection/curation of data and samples, the analysis and interpretation of human genetic and phenotypic data and their translation of derived results to support the discovery and development pipeline for a new generation of differentiated drugs, and in making data in the collections accessible to CEDD - or MDC — initiated questions
We are looking for Medical Genetic Analysts to investigate large-scale genetic/epidemiological studies in a variety of therapeutic/disease areas, as dictated by project requirements
The primary responsibilities for the role will be to:
Apply good statistical genetics or genetic epidemiological knowledge for projects within the disease area as appropriate, delivering analytical and consultative support for design, analysis and interpretation for genetic studies
Manage and manipulate large datasets in preparation for analysis
Independently apply statistical genetics and/or epidemiological expertise to guide and provide accurate and concise summaries, interpretation and communication of genetic results within the group, and to cross-functional project teams
Can be responsible for defining, leading, implementing capability development projects and performing exploratory genetic / genetic epidemiology work to support genetic projects
Maintain good literature awareness of developments in the field so as to be able to apply or provide consultation on the best scientific approaches for design, analysis and interpretation of data
Work with cross-matrix teams (MedGen, other TAs) within the division to support development and implementation of methods to ensure consistency and efficiency for Genetic studies
Work with internal statistical experts (DDS, WWepi, PGX) in and external groups to identify statistical methods, specifically supporting and analyzing whole genome scans.
Basic Qualifications:
The key skills required for this role include:
Degree (or equivalent) in statistics, statistical genetics or genetic epidemiology or related disciplines and interest in statistical genetic analysis and statistical methods development. You will also have related experience in analysis of large data sets
Strong SAS skills (or similar statistical software package), strong programming scripting skills (R, Perl, etc). Should be comfortable working in a UNIX environment and strong ability to manipulate, link and analyse data sets. Knowledge of database applications such as Oracle and Access are also required
Ability to work independently in the design, analysis and interpretation of large scale genetic studies
Clear understanding of the process and technologies of Genetic analysis and /or genetic epidemiology.
Preferred Qualifications:
The following would also be advantageous:
Experience with data mining methods, in particular for psychiatric or behavioural traits and neurological disorders, would be advantageous
Experience in working with longitudinal datasets will be an advantage
Knowledge and understanding of industry and R&D process in drug discovery and development
When applying for this role, please use the ‘cover letter’ of the on-line application to describe how you meet the competencies for this role. Thank you for your interest in this opportunity. The information that you have provided in your cover letter and CV will be used to assess your application
To Apply:
At GSK we provide a supportive working environment, and a range of development challenges and opportunities. We also offer competitive benefits and compensation packages designed to attract and to retain the very best
Alternatively, if you reside in the U.K. and are unable to apply electronically, call 44 (0) 208 047 4777. If you reside in the U.S. and are unable to apply electronically, call 1 888 825 5249
Thank you for taking the time and effort to apply for this role. Please note that we will only contact you again if you are invited to interview All data processed in accordance with the provisions of the Data Protection Act
For a full listing of current opportunities, please visit our website at http://www.gsk.com
GSK is an equal opportunities employer and is proud to promote an open culture, encouraging people to be themselves and giving their ideas a chance to flourish. To enable GSK to meet its commitment as a two ticks employer please let us know if you have a disability









